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Title:
PEPTIDE OR PROTEIN HAVING BINDABILITY TO Fc FRAGMENT OF IgG
Document Type and Number:
Japanese Patent JP2004189657
Kind Code:
A
Abstract:

To provide a novel peptide or protein having bindability to the Fc fragment of IgG and being utilizable for e.g., the purification or detection of IgG.

The Fc fragment of IgG of an animal origin is used as a target substance. The amino acid sequence of a peptide having bindability to the target substance is identified by screening by a pharge display method. A peptide obtained in this way and having an amino acid sequence represented by sequence numbers 1 to 164 or having an amino acid sequence obtained by subjecting to modification or the substitution, insertion, and/or elimination of amino acid residues within the scope not detrimental to the bindability to the Fc fragment of IgG in the amino acid sequence is advantageous in that it can be chemically synthesized and can be prepared in a large quantity at a low cost. Further, it has no risk of e.g. contamination with foreign matter and therefore can be desirably used for e.g. the purification of an antibody especially for medical use.


Inventors:
SUZUKI MASATSUGU
TSUNODA HIROYUKI
KOBAYASHI TOMOMI
MATSUMOTO MEGUMI
Application Number:
JP2002358588A
Publication Date:
July 08, 2004
Filing Date:
December 10, 2002
Export Citation:
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Assignee:
PEPTIDE DOOR CO LTD
International Classes:
C07K7/06; C07K7/08; (IPC1-7): C07K7/06; C07K7/08
Attorney, Agent or Firm:
Shigeru Matsui