AMINE COMPOUND

Japanese Patent JP2009269819

A

To provide a compound that exhibits activity of suppressing immunological response, has reduced side effects, and is useful in chemotherapy for preventing or treating, for example, systemic lupus erythematosus, chronic rheumatoid arthritis, I-type diabetes, an inflammatory bowel disorder, biliary cirrhosis, uveitis, multiple sclerosis, a wide range of various autoimmune diseases including other disorders, chronic inflammatory diseases, cancer, lymphoma, leukemia, or resistance or rejection to a transplant.

Disclosed are a new amine compound having an S1P1/Edg1 receptor agonist action, its possible stereoisomers or lacemates, a pharmacologically acceptable salt thereof, a hydrate thereof, a solvate thereof, and a prodrug thereof.

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OMORI YUTAKA
KOMATSU MASAKAZU

JP2006229187A

November 19, 2009

August 25, 2006

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ASAHI KASEI PHARMA KK

C07D231/56; A61K31/381; A61K31/4025; A61K31/416; A61P1/02; A61P1/04; A61P1/16; A61P1/18; A61P3/10; A61P5/14; A61P7/00; A61P7/04; A61P7/06; A61P9/10; A61P11/00; A61P11/06; A61P13/12; A61P17/00; A61P17/06; A61P17/14; A61P19/02; A61P19/10; A61P21/00; A61P21/04; A61P25/00; A61P25/06; A61P25/28; A61P27/02; A61P27/12; A61P27/16; A61P29/00; A61P31/04; A61P31/12; A61P31/20; A61P35/00; A61P37/02; A61P37/06; A61P37/08; A61P43/00; C07D333/16; C07D409/12

Yoshio Kawaguchi
Makoto Ono
Chihiro Watanabe
Kenkyo Kanayama
Katsuma Osaki
Mitsuaki Tsubokura

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