Title:
アミノ置換ベンゾイル誘導体及びそれらの製造方法と使用
Document Type and Number:
Japanese Patent JP2012503607
Kind Code:
A
Abstract:
A group of amino substituted benzoyl derivatives, their preparation and their use. The screening and research on an antiviral drug with hA3G/Vif as a target point proves that the 3-amino benzoyl derivatives not only have the combined activity for the hA3G/Vif, but also have a function of inhibiting replication of viruses. The present invention provides the possible breakthrough progress for the problem of HIV drug resistance, thereby providing a novel clinical antiviral drug which has higher efficiency.
Inventors:
Jiang Dong Jiang
Yuli Rock
Minamiyama
Lee Takuei
Lee
Xu Jian
Yuli Rock
Minamiyama
Lee Takuei
Lee
Xu Jian
Application Number:
JP2011528163A
Publication Date:
February 09, 2012
Filing Date:
September 28, 2009
Export Citation:
Assignee:
Institute of Medicine and Biotechnology, Chinese Academy of Medical Sciences
International Classes:
C07C237/44; A61K31/136; A61K31/167; A61K31/235; A61K31/255; A61K31/265; A61K31/341; A61K31/40; A61K31/4412; A61K31/505; A61P31/12; C07C231/02; C07C231/12; C07C233/25; C07C233/33; C07C233/54; C07C235/56; C07C303/28; C07C303/38; C07C309/76; C07C311/08; C07C311/29; C07C311/39; C07C311/44; C07C327/28; C07D207/36; C07D213/75; C07D239/47; C07D239/52; C07D307/22
Attorney, Agent or Firm:
Tamio Nishiwaki