Title:
アミノメチル置換されたテトラサイクリン化合物
Document Type and Number:
Japanese Patent JP2005526754
Kind Code:
A
Abstract:
A tetracycline compound having the following formula:
wherein:
J 5 and J 6 are each independently hydrogen, alkyl, alkenyl, alkynyl, aryl, sulfonyl, acyl, substituted carbonyl or substituted thiocarbonyl, or linked to form a ring;
J 7 and J 8 are each alkyl, halogen, or hydrogen;
R 7 dimethylamino; and
R 8 is hydrogen, hydroxyl, halogen, thiol, alkyl, alkenyl, alkynyl, aryl, alkoxy, alkylthio, alkylsulfinyl, alkylsulfonyl, alkylamino, or an arylalkyl, or pharmaceutically acceptable salts thereof.
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Inventors:
Nelson Mark El.
Omen Kashi
Fréchette Roger
Izmail Mohammed Yi.
McIntyre Laura
Bowser Todd
Omen Kashi
Fréchette Roger
Izmail Mohammed Yi.
McIntyre Laura
Bowser Todd
Application Number:
JP2003574133A
Publication Date:
September 08, 2005
Filing Date:
March 10, 2003
Export Citation:
Assignee:
Paratech Pharmaceuticals, Inc.
International Classes:
A61K31/65; A61P1/02; A61P1/04; A61P1/12; A61P1/16; A61P3/10; A61P9/00; A61P9/10; A61P9/12; A61P9/14; A61P11/00; A61P13/02; A61P13/10; A61P15/00; A61P15/14; A61P17/00; A61P17/02; A61P17/16; A61P19/00; A61P19/02; A61P19/08; A61P19/10; A61P21/00; A61P25/00; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P27/02; A61P27/16; A61P29/00; A61P29/02; A61P31/04; A61P31/10; A61P31/12; A61P33/06; A61P35/00; A61P35/02; A61P35/04; A61P37/06; A61P37/08; A61P43/00; C07C237/26; C07C275/34; C07C323/60; C07D207/06; C07D207/16; C07D207/20; C07D207/327; C07D207/335; C07D207/404; C07D209/44; C07D211/58; C07D211/70; C07D213/20; C07D213/56; C07D213/74; C07D213/82; C07D213/89; C07D231/12; C07D233/36; C07D261/10; C07D261/14; C07D261/18; C07D263/22; C07D277/14; C07D277/20; C07D277/42; C07D277/56; C07D295/18; C07D295/20; C07D307/54; C07D317/66; C07D295/14; C07D207/40; (IPC1-7): C07C237/26; A61K31/65; A61P1/02; A61P1/04; A61P1/12; A61P1/16; A61P3/10; A61P9/00; A61P9/10; A61P9/12; A61P9/14; A61P11/00; A61P13/02; A61P13/10; A61P15/00; A61P15/14; A61P17/00; A61P17/02; A61P17/16; A61P19/00; A61P19/02; A61P19/08; A61P19/10; A61P21/00; A61P25/00; A61P25/04; A61P25/08; A61P25/14; A61P25/16; A61P25/18; A61P25/20; A61P25/22; A61P25/24; A61P25/28; A61P27/02; A61P27/16; A61P29/00; A61P29/02; A61P31/04; A61P31/10; A61P31/12; A61P33/06; A61P35/00; A61P35/02; A61P35/04; A61P37/06; A61P37/08; A61P43/00; C07C275/34; C07D207/06; C07D207/16; C07D207/20; C07D207/327; C07D207/335; C07D207/404; C07D209/44; C07D211/58; C07D211/70; C07D213/20; C07D213/56; C07D213/74; C07D213/82; C07D213/89; C07D231/12; C07D233/36; C07D261/10; C07D261/14; C07D261/18; C07D263/22; C07D277/14; C07D277/20; C07D277/42; C07D277/56; C07D295/14; C07D295/18; C07D295/20; C07D307/54; C07D317/66
Domestic Patent References:
| JP2005504722A | 2005-02-17 | |||
| JP2004530661A | 2004-10-07 | |||
| JP2003507439A | 2003-02-25 | |||
| JPS4969653A | 1974-07-05 | |||
| JP2004529927A | 2004-09-30 | |||
| JP2004537544A | 2004-12-16 | |||
| JP2005514410A | 2005-05-19 |
Foreign References:
| WO2002004406A2 | 2002-01-17 | |||
| WO2002004407A2 | 2002-01-17 |
Attorney, Agent or Firm:
Hatsushi Shimizu
Koichi Niimi
Koichi Niimi