Title:
アミノキシ酸系抗がん幹細胞化合物およびその方法
Document Type and Number:
Japanese Patent JP7323238
Kind Code:
B2
Abstract:
The disclosed invention is generally in the field of synthetic small molecules and their use as drug, in particular in the treatment of cancer. Also provided is a method of inhibiting cancer stem cells. Also provided is a method for treatment of cancers and other diseases by affecting mitochondrial functions. Also provided is a method of making and using of the compounds.
Inventors:
Yang Dan
Shen Fang
Shen Fang
Application Number:
JP2022530744A
Publication Date:
August 08, 2023
Filing Date:
November 23, 2020
Export Citation:
Assignee:
WESTLAKE UNIVERSITY
International Classes:
C07C239/20; A61K31/167; A61K31/405; A61K45/00; A61P1/16; A61P15/00; A61P35/00; A61P43/00; C07D209/18
Domestic Patent References:
| JP2018521962A | ||||
| JP2010513332A |
Foreign References:
| WO2006104751A2 | ||||
| WO2019213570A1 |
Other References:
Shen, Fang-Fang et al.,Mediating K+/H+ Transport on Organelle Membranes to Selectively Eradicate Cancer Stem Cells with a Small Molecule,Journal of the American Chemical Society ,2020年,142(24),pp.10769-10779
Yang, Dan et al.,Novel Turns and Helices in Peptides of Chiral α-Aminoxy Acids,Journal of the American Chemical Society,1999年,121(3),pp.589-590
Yang, Dan et al.,Novel Turns and Helices in Peptides of Chiral α-Aminoxy Acids,Journal of the American Chemical Society,1999年,121(3),pp.589-590
Attorney, Agent or Firm:
Patent Attorney Firm WisePlus