Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
ANGIOTENSIN PEPTIDE-CARRIER CONJUGATE, AND USE THEREOF
Document Type and Number:
Japanese Patent JP2010189406
Kind Code:
A
Abstract:

To provide a conjugate including a core particle and one or a plurality of angiotensin peptides or angiotensin peptide moieties, and suitable for use in inducing immune responses.

There is provided the conjugate of a mammalian peptide hormone angiotensinogen, and a peptide derivative of angiotensin I and angiotensin II, presented in a repetitive scaffold by coupling the peptide derivatives to a carrier, particularly a virus-like particle (VLP). Furthermore, there are provided a method for producing the conjugate; and immunotherapeutic use of the resulting immunogen conjugate for therapy and prophylaxis of conditions associated with the renin-activated angiotensin system.


Inventors:
BACHMANN MARTIN
Application Number:
JP2010085112A
Publication Date:
September 02, 2010
Filing Date:
April 01, 2010
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
CYTOS BIOTECHNOLOGY AG
International Classes:
C07K17/00; A61K35/76; A61K38/00; A61K38/095; A61K39/00; A61K39/108; A61K39/12; A61K39/385; A61K39/39; A61P9/00; A61P9/04; A61P9/10; A61P9/12; A61P13/12; A61P37/04; C07K5/113; C07K7/14; C07K14/575; C07K
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori