Title:
ANTI-INFLAMMATORY DRUG CONTAINING 3,7,11-TRIMETHYL-2,6,10-DODECATRIENOIC ACID(2,2-DIMETHYL-1,3-DIOXOLAN-4-YL)METHYL ESTER(KNC-225)
Document Type and Number:
Japanese Patent JPH01160918
Kind Code:
A
Abstract:
PURPOSE:To obtain an anti-inflammatory drug containing 3,7,11-trimethyl-2,6,10- dodecatrienoic acid(2,2-dimethyl-1,3-dioxolan-4-yl)methyl ester (KNC-225). CONSTITUTION:KNC-225 shown by the formula known to show antibacterial actions on Staphylococcus aureus in vitro is used as an active ingredient and pharmaceutically manufactured by a conventional procedure by using a diluent and a carrier to give the aimed substance. The substance can be processed into a dosage form such as powder, tablet, emulsion, capsule, granule, solution, injection, drop, ointment, plaster, fomentation, embrocation, spray, bulky powder, liniment or cream. A dose is 25-500mg calculated as KNC-225 per adult daily in the case of oral preparation, injection and drop and KNC-225 is used in 0.01-10% concentration in the case of parenteral administration of external use.
Inventors:
YAMAHARA JOJI
MORI TOSHIKI
TAMAI HIRONOBU
MORI TOSHIKI
TAMAI HIRONOBU
Application Number:
JP32102787A
Publication Date:
June 23, 1989
Filing Date:
December 17, 1987
Export Citation:
Assignee:
KURARAY CO
International Classes:
C07D317/24; A61K31/335; A61K31/357; A61P29/00; (IPC1-7): A61K31/335; C07D317/24
Attorney, Agent or Firm:
Honda Ken