Title:
形質細胞に対する抗体
Document Type and Number:
Japanese Patent JP2004500070
Kind Code:
A
Abstract:
The present invention relates to a method for producing an antibody, to an antibody specifically reacting with plasma cells, to genes which encode such antibodies, to antigens which are labeled by such an antibody, to additional antibodies directed against said antigens and to methods for producing said antibodies and to uses of such antibodies. In addition, the present invention relates to single-chain multifunctional polypeptides comprising (a) a first domain comprising a binding site of the antibodies defined herein and (b) a second domain comprising a binding site of an immunoglobulin chain or an antibody specifically recognizing the CD3 antigen. Furthermore, compositions and kits comprising the compounds of the invention are disclosed. Preferably said compositions are pharmaceutical or diagnostic compositions.
More Like This:
Inventors:
Muller-Hellmering, Hans, Konrad
Greiner, Accelerator
Dürken, Bernd
Bargow, Ralph
Kufer, Peter
Greiner, Accelerator
Dürken, Bernd
Bargow, Ralph
Kufer, Peter
Application Number:
JP2001549423A
Publication Date:
January 08, 2004
Filing Date:
December 22, 2000
Export Citation:
Assignee:
Muller-Hellmering, Hans, Konrad
Greiner, Accelerator
Greiner, Accelerator
International Classes:
A61K35/76; A61K38/00; A61K39/395; A61K48/00; A61P35/00; A61P37/06; C07K14/47; C07K14/52; C07K16/18; C07K16/28; C07K16/46; C07K19/00; C12N5/10; C12N15/02; C12N15/09; G01N33/53; C12P21/08; A61K39/00; (IPC1-7): C12N15/09; A61K35/76; A61K38/00; A61K39/395; A61K48/00; A61P35/00; A61P37/06; C07K14/47; C07K14/52; C07K16/18; C07K16/46; C07K19/00; C12N5/10; C12N15/02; C12P21/08; G01N33/53
Attorney, Agent or Firm:
Yoshinori Hosoda