PURPOSE: To provide an antidiabetic drug having a strong insulin action or insulin-releasing action and causing no adverse reaction even when administered for a long period by containing as a main ingredient a protein extracted from Euphausiacea with an aqueous solvent and having a specific range of mol.wt.
CONSTITUTION: Euphausiacea is extracted with an aqueous solvent such as cold water, hot water or hydrous ethanol. The obtained extract solution is desalted and dried to give a crude extract, which is subjected to a conventional protein-separating and purifying process to provide an antidiabetic drug containing a protein fraction having a mol.wt. of 20000W40000 as a main ingredient. The preparation is administered, for example, in a dose of 0.1W5g, particularly 1W3g, per day for an adult as the Euphausiacea protein fraction.
MATSUDA REIKO
KOGA KIYOKO
MAKUTA MASAHIRO
SATAKE MIKIO
TAKANE SHUNICHI
CHIBA YOSHIYUKI
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