Title:
APPARATUS AND METHODS FOR ALIQUOTTING FROZEN SAMPLES
Document Type and Number:
Japanese Patent JP2016122018
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To provide apparatus and methods for aliquotting frozen samples.SOLUTION: A method of obtaining an aliquot of a frozen sample contained in a container includes moving a coring device into the sample and then withdrawing the same to obtain a frozen sample core. The location from which the core is taken is selected to be at a radial position where concentration of at least one substance of interest in the frozen sample core is representative of overall concentration of that substance in the sample notwithstanding any concentration gradients that may exist in the frozen sample. Another method includes taking two different frozen sample cores from the same sample from radial positions selected such that the concentration of one or more substances of interest in the combined sample cores is representative of overall concentration of the at least one substance in the sample notwithstanding any radial concentration gradients. A robotic system is programmed or hardwired to implement the methods.SELECTED DRAWING: Figure 2
Inventors:
DALE N LARSON
STEPHEN L BELLIO
JOHN SLUSARZ
STEPHEN L BELLIO
JOHN SLUSARZ
Application Number:
JP2016071584A
Publication Date:
July 07, 2016
Filing Date:
March 31, 2016
Export Citation:
Assignee:
HARVARD COLLEGE
DRAPER LAB CHARLES S
DRAPER LAB CHARLES S
International Classes:
G01N1/28; G01N1/08
Domestic Patent References:
| JP2009524021A | 2009-06-25 | |||
| JPH0360390B2 | 1991-09-13 | |||
| JP2000304664A | 2000-11-02 | |||
| JP2006112847A | 2006-04-27 |
Foreign References:
| US20090101738A1 | 2009-04-23 |
Attorney, Agent or Firm:
Hidesaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto
Natsuki Morishita
Takatoshi Iida
Daisuke Ishikawa
Kensaku Yamamoto