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Title:
AQUEOUS 2,6-DIISOPROPYLPHENOL PHARMACEUTICAL COMPOSITION
Document Type and Number:
Japanese Patent JP2011144161
Kind Code:
A
Abstract:

To provide aqueous pharmaceutical compositions comprising 2,6-diisopropylphenol (propofol).

The aqueous pharmaceutical composition includes propofol and one or more excipients, such as poloxamer, Benzalkonium chloride, Cremophor EL, Deoxycholate, Polyoxyethylene stearate 100, Polysorbate 80, Vitamin E TPGS. The propofol-containing compositions are sterile, are parenterally administered to any animal, including humans, and also chemically and physically stable over a wide range of environmental conditions.


Inventors:
ZHANG ZHONG
ALMARSSON ORN
CHEN HONGMING
Application Number:
JP2010265559A
Publication Date:
July 28, 2011
Filing Date:
November 29, 2010
Export Citation:
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Assignee:
CENTOCOR ORTHO BIOTECH INC
International Classes:
A61K31/05; A61K9/08; A61K47/04; A61K9/10; A61K45/06; A61K47/10; A61K47/12; A61K47/14; A61K47/18; A61K47/22; A61K47/26; A61K47/28; A61K47/34; A61P23/00
Domestic Patent References:
JP2002521434A2002-07-16
JP2005538191A2005-12-15
Foreign References:
WO2000078301A12000-12-28
WO2001097796A12001-12-27
WO2000024376A12000-05-04
WO2001097779A22001-12-27
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Nishino Mitsuru
Mizuhara Masahiro