NEW CRYSTAL OF OPTICALLY ACTIVE 4-AMINO-3-(4-CHLOROPHENYL)BUTANOIC ACID, AND METHOD FOR PRODUCING THE SAME

Title:

NEW CRYSTAL OF OPTICALLY ACTIVE 4-AMINO-3-(4-CHLOROPHENYL)BUTANOIC ACID, AND METHOD FOR PRODUCING THE SAME

Document Type and Number:

Japanese Patent JP2011144162

Kind Code:

A

Abstract:

To provide a new crystal of an optically active 4-amino-3-(4-chlorophenyl)butanoic acid, and a method for producing the same.

This method for producing the following crystal A, comprising a process of heating the following crystal B in water of pH 3 to 9 is provided. Crystal A: the crystal of the optically active 4-amino-3-(4-chlorophenyl)butanoic acid having diffraction peaks in 8.7 to 9.4° range, 12.2 to 12.8° range and 24.8 to 25.4° range diffraction angle 2θ in a powder X-ray diffraction measurement at a Cu-Kα wavelength. Crystal B: the crystal of the optically active 4-amino-3-(4-chlorophenyl)butanoic acid having diffraction peaks in 20.8 to 21.4° range, 26.7 to 27.3° range and 29.7 to 30.3° range diffraction angle 2θ in the powder X-ray diffraction measurement at the Cu-Kα wavelength.

Inventors:

MIKI TAKASHI
TAKEDA MASAO
YAMAZAKI TETSUO

Application Number:

JP2010273298A

Publication Date:

July 28, 2011

Filing Date:

December 08, 2010

Export Citation:

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Assignee:

SUMITOMO CHEMICAL CO

International Classes:

C07C227/42; C07C229/34; C07B57/00

Domestic Patent References:

JP2007332129A	2007-12-27
JP5380743B2	2014-01-08

Foreign References:

WO1997022578A1

1997-06-26

Other References:

JPN6014050890; Ｊｏｕｒｎａｌ　ｏｆ　Ｐｈａｒｍａｃｅｕｔｉｃａｌ　ＳｃｉｅｎｃｅｓＶｏｌ．９６，　Ｎｏ．９, 2007, Ｐ．２３９９-２４０８

Attorney, Agent or Firm:

Toru Nakayama
Toru Sakamoto

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