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Title:
ASSAYING METHOD FOR IDENTIFYING AGENT FOR TREATING FEMALE SEXUAL DYSFUNCTION (FSD), METHOD AND KIT FOR DETECTING FEMALE SEXUAL DYSFUNCTION, AND NON-HUMAN ANIMAL MODEL OF FEMALE SEXUAL DYSFUNCTION
Document Type and Number:
Japanese Patent JP2005013237
Kind Code:
A
Abstract:

To provide an effective method for treating a female suffering from female sexual dysfunction (FSD), in particular, female sexual arousal dysfunction (FSAD).

The method comprises assaying an agent capable of potentiating cAMP in the genital argans of the female suffering from the female sexual dysfunction, in particular, female sexual arousal dysfunction. The agent is an inhibitor of a neutral endopeptidase (I:NEP). The method includes an anesthetized female animal including a means for measuring change in blood flow in the genital organs of the animal accompanied with pelvic nerve stimulation.


Inventors:
MAW GRAHAM NIGEL (GB)
WAYMAN CHRISTOPHER PETER (GB)
Application Number:
JP2004268608A
Publication Date:
January 20, 2005
Filing Date:
September 15, 2004
Export Citation:
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Assignee:
PFIZER (US)
International Classes:
A01K67/027; A61K31/00; A61K31/122; A61K31/137; A61K31/165; A61K31/17; A61K31/18; A61K31/19; A61K31/191; A61K31/192; A61K31/195; A61K31/196; A61K31/197; A61K31/198; A61K31/215; A61K31/216; A61K31/223; A61K31/33; C12N9/99; A61K31/34; A61K31/341; A61K31/352; A61K31/395; A61K31/40; A61K31/4015; A61K31/403; A61K31/404; A61K31/405; A61K31/41; A61K31/4164; A61K31/4166; A61K31/4184; A61K31/421; A61K31/433; A61K31/437; A61K31/438; A61K31/44; A61K31/4402; A61K31/4412; A61K31/4418; A61K31/4425; A61K31/4427; A61K31/443; A61K31/4439; A61K31/444; A61K31/453; A61K31/454; A61K31/4545; A61K31/47; A61K31/4706; A61K31/495; A61K31/496; A61K31/4985; A61K31/499; A61K31/505; A61K31/506; A61K31/517; A61K31/519; A61K31/52; A61K31/522; A61K31/53; A61K31/548; A61K31/55; A61K31/551; A61K31/553; A61K31/554; A61K31/65; A61K31/661; A61K31/675; A61K38/00; A61K38/12; A61K38/46; A61K38/55; A61K45/00; A61P5/30; A61P9/14; A61P15/00; A61P15/02; A61P15/08; A61P15/12; A61P25/02; A61P43/00; C07C233/58; C07C233/60; C07C311/51; C07D207/26; C07D207/27; C07D209/12; C07D213/64; C07D213/74; C07D213/75; C07D213/80; C07D213/85; C07D215/40; C07D223/10; C07D223/16; C07D233/72; C07D233/78; C07D239/95; C07D251/48; C07D257/06; C07D263/34; C07D267/14; C07D285/135; C07D295/02; C07D295/08; C07D307/14; C07D307/24; C07D307/54; C07D401/04; C07D401/12; C07D403/06; C07D471/14; C07D473/30; C07D473/34; C07D487/04; C07D513/04; C07K14/47; C07K14/705; C12N9/64; C12N9/88; C12N15/09; C12Q1/37; C12Q1/42; C12Q1/44; C12Q1/68; G01N33/15; G01N33/50; G01N33/53; G01N33/573; G01N33/68; A61K; (IPC1-7): C12Q1/37; A01K67/027; A61K31/19; A61K31/192; A61K31/4015; A61K31/433; A61K31/4412; A61K45/00; A61P5/30; A61P15/00; A61P15/12; A61P43/00; G01N33/15; G01N33/50
Attorney, Agent or Firm:
Kazuo Shamoto
Tadashi Masui
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Kiyoshi Murakami