Title:
細胞壁結合セラミド様糖脂質による細菌ワクチンおよびその使用
Document Type and Number:
Japanese Patent JP6469173
Kind Code:
B2
Abstract:
The invention is directed compositions and methods related to bacterial cells physically associated with ceramide-like glycolipids. The invention allows for delivery of ceramide-like glycolipid adjuvants directly to the same cells that become infected with a bacterial vaccine. The compositions and methods of the present invention are useful for the prevention and treatment of diseases.
Inventors:
Porseri Steven A.
Benka Swami Manjunata Em.
Benka Swami Manjunata Em.
Application Number:
JP2017121122A
Publication Date:
February 13, 2019
Filing Date:
June 21, 2017
Export Citation:
Assignee:
Albert Einstein College of Medicine, Incorporated
International Classes:
C12N1/20; A61K9/19; A61K35/74; A61K39/02; A61K39/04; A61K39/39; A61K47/26; A61K47/51; A61P11/00; A61P17/00; A61P31/04; A61P31/06; A61P31/10; A61P31/12; A61P31/14; A61P31/18; A61P31/20; A61P33/00; A61P33/06; A61P35/00; A61P37/04; C12N1/21; A61K39/00
Domestic Patent References:
| JP2008511634A | ||||
| JP2005500336A |
Foreign References:
| WO2008133801A1 | ||||
| US20060019246 |
Other References:
J. CLIN. INVEST.,2006年 6月,Vol. 116, No. 6,P. 1660-1667
Journal of Clinical Oncology,1994年,Vol. 12, No. 15,pp. 1036-1044
British Journal of Cancer,2014年10月14日,Vol. 111,p. 1945-1954
Journal of Clinical Oncology,1994年,Vol. 12, No. 15,pp. 1036-1044
British Journal of Cancer,2014年10月14日,Vol. 111,p. 1945-1954
Attorney, Agent or Firm:
Hatsushi Shimizu
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto
Masao Haruna
Hirotaka Yamaguchi
Toshi Gobe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Masato Ozeki
Yoshihiro Igarashi
Kazuya Kawamoto