PURPOSE: To obtain the subject preparation suitable for functional diagnosis of digestive canal, not causing aggregation precipitation in the digestive canal even after administration, mobile without obstructing motion of digestive canal due to maintenance of granular state, by using a specific copolymer as a binder or a coating agent.

CONSTITUTION: This preparation is obtained by using a copolymer of ethyl acrylate and methyl methacrylate as a binder or a coating agent. The preparation is preferably obtained by adding (B) barium sulfate powder to (B) an emulsion prepared by dispersing the copolymer of ethyl acrylate and methyl methacrylate to water, kneading, granulating and drying. The particle diameter of the component A is preferably 500μm to 5mm. When the component B is used as the binder, 5-15 pts.wt. of the component B is used based on 100 pts.wt. of the component A. When the component B is used as the coating agent, 0.2-3 pts.wt. of the component B is preferably used based on 100 pts.wt. of the component A.