Title:
ベンゼンスルホンアミド誘導体
Document Type and Number:
Japanese Patent JP5208412
Kind Code:
B2
Abstract:
The present invention relates to a benzenesulfonamide derivative of formula (I), which is useful as an active ingredient of pharmaceutical preparations. The benzenesulfonamide derivatives of the present invention have CCR3 (CC type chemokine receptor) antagonistic activity, and can be used for the prophylaxis and treatment of disease associated with CCR3 activity, in particular for the treatment of asthma, atopic dermatitis, allergic rhinitis and other inflammatory/immunological disorders.
wherein
X represents O or S;
R 4 represents
the other substituents are as defined in claim 1.
Inventors:
Li, Inf
Bacon, kevin
Sugimoto, Hiromi
Fukushima, Keiko
Hashimoto, Centaro
Marumo, Makiko
Moriwaki, Toshiya
Nunami, Noriko
Tsuno, Naoki
Jurvans, Claus
Yoshida, Nagahiro
Bacon, kevin
Sugimoto, Hiromi
Fukushima, Keiko
Hashimoto, Centaro
Marumo, Makiko
Moriwaki, Toshiya
Nunami, Noriko
Tsuno, Naoki
Jurvans, Claus
Yoshida, Nagahiro
Application Number:
JP2006504635A
Publication Date:
June 12, 2013
Filing Date:
March 11, 2004
Export Citation:
Assignee:
Akshikin Pharmaceuticals, Inc.
International Classes:
C07C311/29; A61K31/275; A61K31/336; A61K31/4015; A61K31/4025; A61K31/405; A61K31/41; A61K31/439; A61K31/4453; A61K31/4465; A61K31/454; A61K31/495; A61K31/496; A61K31/4965; A61K31/497; A61K31/551; A61P11/02; A61P11/06; A61P25/28; A61P29/00; A61P31/18; A61P35/00; A61P37/06; A61P37/08; A61P43/00; C07C311/37; C07D207/12; C07D207/14; C07D207/16; C07D207/34; C07D207/40; C07D207/404; C07D207/48; C07D211/54; C07D223/12; C07D241/04; C07D243/08; C07D257/04; C07D295/12; C07D295/13; C07D295/22; C07D295/26; C07D303/06; C07D303/48; C07D401/04; C07D401/06; C07D403/04; C07D403/06; C07D453/02; C07D487/04; C07F7/18
Domestic Patent References:
| JP2003081937A | ||||
| JP2004217654A | ||||
| JP2005509032A | ||||
| JP2003512355A | ||||
| JP2003535079A | ||||
| JP2004516237A |
Foreign References:
| WO2003022277A1 |
Attorney, Agent or Firm:
Toru Ishikawa