Title:
生物工学的組織構築物およびそれを生成および使用する方法
Document Type and Number:
Japanese Patent JP5484975
Kind Code:
B2
Abstract:
Cultured tissue constructs comprising cultured cells and endogenously produced extracellular matrix components without the requirement of exogenous matrix components or network support or scaffold members. Some tissue constructs of the invention are comprised of multiple cell layers or more than one cell type. The tissue constructs of the invention have morphological features and functions similar to tissues and their strength makes them easily handleable. Preferred cultured tissue constructs of the invention are prepared in defined media, that is, without the addition of chemically undefined components.
Inventors:
Murphy, Michael, Pee.
Ronfurd, Vincent
Ronfurd, Vincent
Application Number:
JP2010065679A
Publication Date:
May 07, 2014
Filing Date:
March 23, 2010
Export Citation:
Assignee:
Organogenesis ink.
International Classes:
C12N5/071; C12N15/09; A61K35/12; A61K35/22; A61K35/32; A61K35/36; A61K35/38; A61K35/42; A61K35/44; A61L27/00; A61P17/00; A61P17/02; A61P17/06; A61P43/00
Domestic Patent References:
JP64010983A | ||||
JP8038165A | ||||
JP10508522A |
Foreign References:
WO1996039101A1 | ||||
US5665391 |
Other References:
新生化学実験講座18 細胞培養技術,株式会社 東京化学同人,1995年 7月 1日,p.27-29
組織培養研究,1992年,Vol.11, No.3,p.337-343
Proc.Natl.Acad.Sci.USA,1981年,Vol.78,p.2879-2882
Brit.J.Haematol.,1996年,Vol.92,p.77-87
J.Invest.Dermatol.,1995年,Vol.104,p.989-994
組織培養研究,1992年,Vol.11, No.3,p.337-343
Proc.Natl.Acad.Sci.USA,1981年,Vol.78,p.2879-2882
Brit.J.Haematol.,1996年,Vol.92,p.77-87
J.Invest.Dermatol.,1995年,Vol.104,p.989-994
Attorney, Agent or Firm:
Hiroe Associates Patent Office
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