Title:
BIOTECHNOLOGICAL PREPARATION OF CYCLIC S-ALPHA-AMINOCARBOXYLIC ACID AND R-ALPHA-AMINOCARBOXAMIDE
Document Type and Number:
Japanese Patent JP3694065
Kind Code:
B2
Abstract:
PURPOSE: To prepare a new microorganism having the ability to convert an (RS)-α-aminocarboxamide into an S-α-aminocarboxylic acid and capable of separating the product in a high enantiomeric purity.
CONSTITUTION: This microorganism is capable of utilizing an α- aminocarboxamide in the form of a racemate or its optically active isomer represented by formula I [A together with NH and CH forms a (substituted)5- to 6-membered saturated heterocyclic ring] as a sole nitrogen source and converting the (RS)-α-aminocarboxamide represented by formula I into an S-α- aminocarboxylic acid represented by formula II and preferably belongs to the genus Klebsiella or Pseudomonas.
Inventors:
Andreas Keener
Jean-Paul Rodui
Jörg Cole
Nicholas Shaw
Jean-Paul Rodui
Jörg Cole
Nicholas Shaw
Application Number:
JP14068495A
Publication Date:
September 14, 2005
Filing Date:
June 07, 1995
Export Citation:
Assignee:
LONZA LIMITED
International Classes:
C12N1/20; C12P17/00; C12P17/10; C12P17/12; C12P41/00; C12R1/22; C12R1/38; C12R1/39; C12R1/40; (IPC1-7): C12N1/20; C12P41/00
Domestic Patent References:
| JP530992A | ||||
| JP5294486A | ||||
| JP2501531A |
Foreign References:
| EP0383403A1 |
Attorney, Agent or Firm:
Takehiko Suzue
Sadao Muramatsu
Atsushi Tsuboi
Ryo Hashimoto
Toshio Shirane
Sadao Muramatsu
Atsushi Tsuboi
Ryo Hashimoto
Toshio Shirane