Title:
ベンゾオキサゾールアリールアミドから誘導されたCETP阻害剤
Document Type and Number:
Japanese Patent JP2010530417
Kind Code:
A
Abstract:
Compounds having the structure of Formula I, including pharmaceutically acceptable salts of the compounds, are potent CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis. In formula I, A-B is an arylamide moiety.
Inventors:
Hunt, The Julianne A
Swiss, Ramsey Eff
Martinez, Rogelio El
Sinclair, Peter Theei
Swiss, Ramsey Eff
Martinez, Rogelio El
Sinclair, Peter Theei
Application Number:
JP2010513203A
Publication Date:
September 09, 2010
Filing Date:
June 16, 2008
Export Citation:
Assignee:
Merck Sharp End Dome Corporation
International Classes:
C07D263/56; A61K31/423; A61K31/427; A61K31/4439; A61K31/454; A61K31/496; A61K31/5377; A61K45/00; A61P3/06; A61P9/10; A61P43/00; C07D413/12; C07D417/12
Domestic Patent References:
| JP2001512416A | 2001-08-21 | |||
| JPS615071A | 1986-01-10 | |||
| JPH10510513A | 1998-10-13 | |||
| JP2002536333A | 2002-10-29 | |||
| JP2003503390A | 2003-01-28 |
Foreign References:
| WO2003066579A2 | 2003-08-14 | |||
| US4714762A | 1987-12-22 | |||
| WO1997043255A1 | 1997-11-20 |
Attorney, Agent or Firm:
Yoshio Kawaguchi
Chihiro Watanabe
Katsuma Osaki
Mitsuaki Tsubokura
Chihiro Watanabe
Katsuma Osaki
Mitsuaki Tsubokura