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Title:
CETP阻害薬
Document Type and Number:
Japanese Patent JP5301999
Kind Code:
B2
Abstract:
Compounds of Formula I, including pharmaceutically acceptable salts of the compounds, are CETP inhibitors, and are useful for raising HDL-cholesterol, reducing LDL-cholesterol, and for treating or preventing atherosclerosis.

Inventors:
Ali, Amjiyad
Hunt, The Julianne A
Karasi, Florida
Kovarchitsk, Jennier Y
Kim, Dousop
Smith, Cameron Jei
Sinclair, Peter Theei
Swiss, Ramsey Eff
Taylor, Gale E
Thompson, Christopher Eff
Chien, rear
Clichy, Natsuia
Application Number:
JP2008538054A
Publication Date:
September 25, 2013
Filing Date:
October 30, 2006
Export Citation:
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Assignee:
Merck Sharp & Dohme Corp.
International Classes:
C07D263/56; C07D413/12; C07D413/14; C07D471/04; C07D471/10; C07D487/04; C07D495/10; A61K31/155; A61K31/423; A61K31/4439; A61K31/454; A61K31/4709; A61K31/496; A61K31/4985; A61K31/5377; A61K31/55; A61K31/64; A61K31/695; A61K38/28; A61K45/00; A61P9/10; A61P43/00; C07D235/18; C07D239/74; C07D277/66; C07D413/04; C07D413/10
Domestic Patent References:
JP10158116A
JP53105529A
JP2005525378A
JP2004501863A
JP2002518985A
JP2005514382A
JP2005521666A
Foreign References:
WO2005100298A1
WO2005044807A1
WO2005033288A1
WO2005000833A1
WO2006108965A1
US5104960
US3135762
DE3818986A
Other References:
Bioorg. Med. Chem. Lett.,2001年,11,1545-1548
Attorney, Agent or Firm:
Yoshikazu Iwase
Makoto Ono
Kenkyo Kanayama
Mitsuaki Tsubokura
Kazuki Shigemori
Kenji Ando
Yasufumi Shiroyama