PURPOSE: To obtain a new salt useful for treatment of gastrointestinal disorders such as peptic ulcer, gastritis and nonulser dyspepsia.
CONSTITUTION: This compd. is a complex salt of a basic histamine H2-receptor antagonist expressed by formula I and a carboxylic acid selected from tartaric acid, citric acid with an alkylcitric acid. In formula I, R1 is formula II (R3 is methyl, etc.); R2 is H, methyl; X is O (in that case, n=3) or S, CH2 (in that case, n=2). The compd. is, for example, N[3[[5[(dimethylamino) methyl]2- furanyl]methoxy] propylN'-methyl2-nitro1,1-ethene diamine=2hydroxy-1, 2,3-propane tricarboxylate bismuth (3+) complex and its solvates. This salt is obtd. by the reaction of a furan deriv. expressed by formula I and a bismuth complex of carboxylic acid selected from tartaric acid, citric acid and alkylcitric acid in a solvent such as water.
JIYON WATOSON KURISUROO
DEIBITSUDO EDOMUNDO BEISU
