Title:
カロテノイド誘導体、その薬学上許容される塩又はその薬学上許容されるエステル類若しくはアミド類
Document Type and Number:
Japanese Patent JP6393754
Kind Code:
B2
Abstract:
The object of the present invention is to find a carotenoid compound that is excellent in water solubility. A carotenoid derivative having a formula (I):
wherein
X represents a carbonyl group or a methylene group, one of R 1 and R 2 represents (a) or (b) and the other represents (a), (b), (c) or a hydrogen atom:
(a): -CO-A-B-D wherein A represents an alkylene group an alkenylene group, etc., B represents a formula of -S(O) n - or a formula of -NR 4 CONR 5 - and D represents a hydrogen atom, a carboxy group, etc.,
(b): -CO-E-F wherein E represents an alkylene group or a formula of -NR 3 - wherein R 3 represents (a1) a hydrogen atom, (b1) an alkyl group etc., and F represents a sulfo group and
(c): -CO-G wherein G represents a hydrogen atom, an alkyl group, 1 etc.,
a pharmaceutically acceptable salt thereof, or a pharmaceutically acceptable ester or amide thereof.
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Inventors:
Gack Fujita
Kobayashi
Ryoma Shinohara
Yasuhiro Nishida
Jiro Takahashi
Kobayashi
Ryoma Shinohara
Yasuhiro Nishida
Jiro Takahashi
Application Number:
JP2016521120A
Publication Date:
September 19, 2018
Filing Date:
May 20, 2015
Export Citation:
Assignee:
Asta Pharmaceuticals Co., Ltd.
International Classes:
C07C403/24; A61K31/215; A61K31/22; A61K31/4178; A61P3/00; A61P3/10; A61P9/00; A61P9/10; A61P21/00; A61P25/18; A61P25/24; A61P25/28; A61P27/02; A61P27/04; A61P27/06; A61P39/06; C07D233/61
Domestic Patent References:
| JP2013518856A | ||||
| JP2010248243A | ||||
| JP2006517197A | ||||
| JP2005517010A |
Foreign References:
| WO2006105214A1 | ||||
| WO2008118862A1 | ||||
| WO2008106606A1 | ||||
| WO2006119168A1 | ||||
| WO2006099015A1 | ||||
| WO2005102356A1 |
Other References:
Biological & Pharmaceutical Bulletin,2002年,25(3),p.390-392
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation
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