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Title:
細胞培養監視システム
Document Type and Number:
Japanese Patent JP7268249
Kind Code:
B2
Abstract:
A cell culture monitoring system (1) comprising a monitoring apparatus (3) for coupling to a culture tank (2) containing a cell culture medium (15) therein, and a fluid circulation system (4) for fluidic coupling to the cell culture tank (2) the fluid circulation system comprising a dielectrophoresis cartridge (5) for connection to the cell culture tank (2) via supply and return conduits (14a), (14b), the dielectrophoresis cartridge comprising a base (20) and an electrode support (19) having electrodes (21) in or on the electrode support (19), the electrodes configured for travelling wave dielectrophoresis and comprising a measurement zone (21a) arranged above a measuring chamber (23b) formed between the electrode support (19) and a floor (26) of the base (20) forming a measuring chamber therebetween, whereby cells in a liquid medium flowing through the measuring chamber are subject to a travelling wave dielectrophoresis force orthogonal to a direction of flow of said liquid through said measuring chamber (23b), the monitoring apparatus (3) comprising a computing unit (9), an image capture system (7) connected to the computing unit (9), and a cartridge holder portion (28) for receiving said dielectrophoresis cartridge (5) such that the image capture system (7) may detect cells flowing through said measuring chamber (23b).

Inventors:
Leonard Ballas
Sebastian Walpen
Application Number:
JP2022526452A
Publication Date:
May 02, 2023
Filing Date:
November 03, 2020
Export Citation:
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Assignee:
Saydos Esa
International Classes:
C12M1/34; C12Q1/02
Domestic Patent References:
JP2016133314A
Foreign References:
WO2010113994A1
EP3196631A1
Attorney, Agent or Firm:
Murayama Yasuhiko
Shinya Mihiro
Tatsuhiko Abe