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Title:
細胞培養基材
Document Type and Number:
Japanese Patent JP6493629
Kind Code:
B2
Abstract:
The present invention provides a cell culture substrate including a polymer having a lower critical solution temperature, the substrate including one or more inorganic materials selected from a water-swellable clay mineral and silica and further including an adhesive matrix in the substrate, in which the adhesive matrix is an extracellular matrix and/or an adhesive synthetic matrix. Furthermore, the invention is to provide a cell culture substrate in which the extracellular matrix is at least one selected from laminin, fibronectin, vitronectin, cadherin, and fragments thereof, and/or the adhesive synthetic matrix is poly[2-(methacryloyloxy)ethyl dimethyl-(3-sulfopropyl) ammonium hydroxide] or an oligopeptide-supporting polymer.

Inventors:
Tetsuo Takada
Naoto Sakurai
Ayako Isshiki
Noriko Shandong
Application Number:
JP2018535907A
Publication Date:
April 03, 2019
Filing Date:
December 12, 2017
Export Citation:
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Assignee:
DIC Corporation
International Classes:
C12M3/00; C08L33/14; C08L33/26; C08L77/00; C08L89/00; C12N5/00
Domestic Patent References:
JP2015165921A
JP2016039806A
JP2013194084A
JP2010017128A
JP2015519902A
JP2016194054A
JP2016193976A
JP2014108093A
Foreign References:
WO2010027081A1
WO2015093393A1
Other References:
高分子学会予稿集,2006年,Vol.55, No.2,p.2PB128,全文
Biotechnol. Bioeng.,2009年,Vol.103, No.2,pp.370-377,Figure1
J. Mater. Chem.,2011年,Vol.21,pp.6883-6890,Figs. 1,2,4,p.6885右欄
Attorney, Agent or Firm:
Shinji Ogawa
Akihiro Iwamoto
Takayuki Ohno
Makoto Negishi