Title:
CHIRAL AUXILIARY GROUPS
Document Type and Number:
Japanese Patent JP2019006793
Kind Code:
A
Abstract:
To provide novel compounds that can act as auxiliary groups for asymmetric induction in manufacture of phosphorus atom-modified nucleic acid derivatives.SOLUTION: The present invention provides chiral auxiliary groups useful for efficiently manufacturing phosphorus atom-modified nucleic acid derivatives with high stereoregularity; and compounds for introducing the chiral auxiliary groups represented by general formula (I) or (XI) in the figure.SELECTED DRAWING: None
Inventors:
WADA TAKESHI
SHIMIZU MAMORU
SHIMIZU MAMORU
Application Number:
JP2018154836A
Publication Date:
January 17, 2019
Filing Date:
August 21, 2018
Export Citation:
Assignee:
WAVE LIFE SCIENCES LTD
International Classes:
C07D207/12; C07B57/00; C07D209/62; C07D217/24; C07D221/10; C07D221/18; C07F9/6539; C07H21/02; C07H21/04
Attorney, Agent or Firm:
Takayuki Hirose
Daisuke Seki
Daisuke Seki