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Title:
メチル化DNA分離及び/又は検出用クロマトグラフィー用充填剤
Document Type and Number:
Japanese Patent JP6570795
Kind Code:
B2
Abstract:
Provided is a chromatography packing that can detect methylated DNA with high accuracy. An ion-exchange chromatography packing for separation and/or detection of methylated DNA, containing a base particle consisting of a hydrophobic crosslinked copolymer particle having a cationic functional group on a surface, wherein a hydrophobic crosslinked copolymer contains a divinyl aromatic monomer.

Inventors:
Takuya Yotani
Kohei Matsuda
Application Number:
JP2019523131A
Publication Date:
September 04, 2019
Filing Date:
August 27, 2018
Export Citation:
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Assignee:
Sekisui Medical Co., Ltd.
International Classes:
B01J20/285; B01D15/36; B01J20/281; G01N30/02; G01N30/88
Domestic Patent References:
JP4317740A
Foreign References:
WO2014136930A1
WO2016117572A1
WO2016205233A2
WO2016024634A1
Other References:
IGLESIAS, T. et al.,ANALYTICAL AND BIOANALYTICAL CHEMISTRY,2015年,Vol.407, No.9,pp.2423-2431
WIEDER, W. et al.,JOURNAL OF SEPARATION SCIENCE,2006年,Vol.29,pp.2478-2484
Attorney, Agent or Firm:
Alga Patent Office, a patent business corporation