CL-1957 B ANTIBACTERIAL COMPOUND AND MANUFACTURE

Title:

CL-1957 B ANTIBACTERIAL COMPOUND AND MANUFACTURE

Document Type and Number:

Japanese Patent JPS60120874

Kind Code:

A

Abstract:

A purified isolate of an actinomycete identified as ATCC 39366 is capable of producing the antimicrobial compound CL-1957B which also exhibits antitumor properties. The antimicrobial compound CL-1957B is produced by cultivating isolate ATCC 39366 under aerobic conditions in a culture medium containing assimilable sources of carbon and nitrogen until a substantial quantity of the CL-1957B compound is produced, and subsequently isolating the compound. The antibiotic compound CL-1957B, its pharmaceutically acceptable salts, and pharmaceutical compositions comprising this substance together with a pharmaceutically acceptable carrier is also disclosed, as are methods of treating microbial infections and tumors in mammals, employing these pharmaceutical compositions.

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Inventors:

JIERAADO SHII HOUKANSON
JIYON PII SHIYOOMUBAAGU
JIEIMUZU SHII FURENCHI
JIYOZEFUINO BII TANATSUKU

Application Number:

JP18897784A

Publication Date:

June 28, 1985

Filing Date:

September 11, 1984

Export Citation:

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Assignee:

WARNER LAMBERT CO

International Classes:

A61K31/365; A61P31/04; A61P35/00; C07D309/22; C07D309/32; C12P1/06; C12P17/06; C12R1/01; (IPC1-7): A61K31/365; C07D309/32; C12P1/06; C12P17/06; C12R1/01

Attorney, Agent or Firm:

Chika Takagi

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