Title:
共結晶化法
Document Type and Number:
Japanese Patent JP4896294
Kind Code:
B2
Abstract:
A process for isolating enantiomer components from a mixture of enantiomers through co-crystallization is disclosed, comprising the steps of (a) forming a solution comprising the mixture of enantiomers (R) and (S) and co-crystallization agents C1 and C2, wherein C1 and C2 are chiral or achiral, with the proviso that at least one of C1 and C2 is chiral and C1 and C2 do not form an enantiomeric pair, whereby C1 forms a co-crystal with (R) and C2 forms a co-crystal with (S); (b) super-saturating the solution in C1 * (R) and C2 * (S); (c) inducing crystallization of co-crystals of C1 * (R) and C2 * (S); and (d) isolating the C1 * (R) co-crystals and C2 * (S) co-crystals.
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Inventors:
Karl Reuter
Application Number:
JP2000603771A
Publication Date:
March 14, 2012
Filing Date:
March 03, 2000
Export Citation:
Assignee:
Reuters Chemiche Appalatebau Commande Gesellschaft
International Classes:
C07B57/00; B01D9/02; C07C209/88; C07C211/58; C07C303/42; C07C303/44; C07C309/19
Domestic Patent References:
| JPS5686138A | 1981-07-13 | |||
| JPS5655360A | 1981-05-15 | |||
| JP2000506066A | 2000-05-23 |
Attorney, Agent or Firm:
Junji Yuda
Chika Takagi
Kosuke Nishimura
Chika Takagi
Kosuke Nishimura