Title:
成体臓器幹細胞の組成物およびその使用
Document Type and Number:
Japanese Patent JP2013541541
Kind Code:
A
Abstract:
Compositions of isolated adult organ stem cells, including hematopoietic stem cells, cardiac stem cells, and kidney stem cells, are disclosed. In particular, the present invention provides c-kit positive, lineage negative adult stem cells that can be isolated from adult organ tissue. Such stem cells are capable of generating all the cell lineages of the organ tissue from which they were isolated. Methods for repairing damaged organ tissue with the isolated organ stem cells are also disclosed.
Inventors:
Ambelsa, clown
Application Number:
JP2013532917A
Publication Date:
November 14, 2013
Filing Date:
October 05, 2011
Export Citation:
Assignee:
NEW YORK MEDICAL COLLEGE
International Classes:
A61K35/12; A61K35/23; A61K35/34; A61L27/00; A61P13/12; C12N5/074; C12N15/00; C12N15/09
Foreign References:
| US20090306625A1 | 2009-12-10 | |||
| US20070065942A1 | 2007-03-22 |
Other References:
JPN6015042238; Ｐｅｄｉａｔｒ Ｎｅｐｈｒｏｌ ２３, 2008, ８５１-８６１
JPN6015042241; 透析会誌 ４０， ９, 2007, ７６３-７６８
JPN6015042242; ＰＬＯＳ ｏｎｅ ５， １２, 201012, ｅ１４３８６
JPN6015042244; Ｊ Ａｍ Ｓｏｃ Ｎｅｐｈｒｏｌ １４, 2003, １１８８-１１９９
JPN6015042246; Ｊ Ａｍ Ｓｏｃ Ｎｅｐｈｒｏｌ １７, 2006, ３３００-３３１４
JPN7015002889; ＢＡＳＵ， Ｊ． ｅｔ ａｌ．: 'Ｄｉｓｔｒｉｂｕｔｉｏｎ ａｎｄ ａｎａｌｙｓｉｓ ｏｆ ｓｔｅｍ ａｎｄ ｐｒｏｇｅｎｉｔｏｒ ｃｅｌｌ ｐｏｐｕｌａｔｉｏｎｓ ｉｎ ｌａｒｇｅ ｍａｍｍａｌ ａｎｄ ｈｕｍａｎ ｋｉｄｎｅｙｓ' Ｔｈｅ ＦＡＳＥＢ Ｊｏｕｒｎａｌ ２４（ｍｅｅｔｉｎｇ ａｂｓｔｒａｃｔ ｓｕｐｐｌｅｍｅｎｔ）, 201004, ｌｂ３５
JPN6015042236; Ａｎｎａｌｓ ｏｆ Ｏｎｃｏｌｏｇｙ １４, 2003, ８９４-８９７
JPN6015042241; 透析会誌 ４０， ９, 2007, ７６３-７６８
JPN6015042242; ＰＬＯＳ ｏｎｅ ５， １２, 201012, ｅ１４３８６
JPN6015042244; Ｊ Ａｍ Ｓｏｃ Ｎｅｐｈｒｏｌ １４, 2003, １１８８-１１９９
JPN6015042246; Ｊ Ａｍ Ｓｏｃ Ｎｅｐｈｒｏｌ １７, 2006, ３３００-３３１４
JPN7015002889; ＢＡＳＵ， Ｊ． ｅｔ ａｌ．: 'Ｄｉｓｔｒｉｂｕｔｉｏｎ ａｎｄ ａｎａｌｙｓｉｓ ｏｆ ｓｔｅｍ ａｎｄ ｐｒｏｇｅｎｉｔｏｒ ｃｅｌｌ ｐｏｐｕｌａｔｉｏｎｓ ｉｎ ｌａｒｇｅ ｍａｍｍａｌ ａｎｄ ｈｕｍａｎ ｋｉｄｎｅｙｓ' Ｔｈｅ ＦＡＳＥＢ Ｊｏｕｒｎａｌ ２４（ｍｅｅｔｉｎｇ ａｂｓｔｒａｃｔ ｓｕｐｐｌｅｍｅｎｔ）, 201004, ｌｂ３５
JPN6015042236; Ａｎｎａｌｓ ｏｆ Ｏｎｃｏｌｏｇｙ １４, 2003, ８９４-８９７
Attorney, Agent or Firm:
Yoshiyuki Inaba
Toshifumi Onuki
Toshifumi Onuki