Title:
成長因子モジュレーションのための組成物および方法
Document Type and Number:
Japanese Patent JP6796695
Kind Code:
B2
Abstract:
Provided herein are proteins, antibodies, assays and methods useful for modulating growth factor levels and/or activities. In some embodiments, such growth factors are members of the TGF-β superfamily of proteins.
Inventors:
Schulf, Thomas
Mahan Sappa, Nagesh Kay.
Straub, Michelle Marie
Mahan Sappa, Nagesh Kay.
Straub, Michelle Marie
Application Number:
JP2019161176A
Publication Date:
December 09, 2020
Filing Date:
September 04, 2019
Export Citation:
Assignee:
SCHOLAR ROCK,INC.
International Classes:
C12N15/13; A61K38/18; A61K38/39; A61K39/395; A61P1/16; A61P3/10; A61P9/00; A61P11/00; A61P13/12; A61P17/00; A61P17/02; A61P19/02; A61P21/00; A61P21/02; A61P25/00; A61P31/04; A61P35/00; A61P37/02; A61P43/00; C07K14/47; C07K16/18; C07K16/46; C12N15/12; C12N15/62; C12Q1/04; G01N33/53; G01N33/543
Other References:
宮園浩平ほか編, 実験医学別冊BioScience用語ライブラリー サイトカイン・増殖因子, 1997年5月, 株式会社
Mol. Biol. Cell (2012) vol.23, vol.6, p.1129-1139
J. Cell Biol. (1997) vol.136, no.5, p.1151-1163
Manuela Battaglia,The Tregs' world according to GARP,Eur. J. Immunol.,2009年,39,p.3296-3300
Mol. Biol. Cell (2012) vol.23, vol.6, p.1129-1139
J. Cell Biol. (1997) vol.136, no.5, p.1151-1163
Manuela Battaglia,The Tregs' world according to GARP,Eur. J. Immunol.,2009年,39,p.3296-3300
Attorney, Agent or Firm:
Masahiro Nanjo
Ayako Seta
Koichiro Inami
Hidetoshi Hara
Ayako Seta
Koichiro Inami
Hidetoshi Hara