Login| Sign Up| Help| Contact|

Patent Searching and Data


Title:
COMPOUND HAVING IMMUNOMODULATIVE ACTIVITY
Document Type and Number:
Japanese Patent JPH11269189
Kind Code:
A
Abstract:

To obtain a compound expressed by a specific structural formula and useful as therapeutic agents for marrow suppression caused by the administration of antitumor agents and anticancer agents based on their immunopotentiative actions and radiation therapy, inflammatory diseases, immunodeficiency diseases and autoimmunodeficiency diseases such as chronic rheumatoid arthritis as an immunomodulator.

This compound is expressed by a structural formula: a monosaccharide → Gall → 1' Cer (C24, Sat.). The monsaccharide is bound to 3, 4 and 6 positions of Gal with glycoside bonds and preferably selected from the group comprising Fuc, Gal, and Rha. The compound is preferably expressed by the structural formula: Fuc β1 → 3Gal α1 → 1' Cer (C24, Sat.), Fuc β1 →4 (Fuc α1 → 3) Gal α1 → 1' Cer (C24, Sat.), Fuc β1 → 6 Gal α1 → 1' Cer (C24, Sat.), or the like. The compound is preferably administered in a daily dose of 0.1-100 mg for an adult.


Inventors:
NUNOMURA SHIGEKI
OSAWA RYOICHI
ENDO AKIRA
SUDA ISAO
Application Number:
JP9235398A
Publication Date:
October 05, 1999
Filing Date:
March 19, 1998
Export Citation:
Click for automatic bibliography generation   Help
Assignee:
NISSIN FOOD PRODUCTS LTD
International Classes:
C07H15/10; A61K31/70; A61K31/7028; A61P35/00; A61P37/00; A61P37/04; C07H15/04; (IPC1-7): C07H15/10; A61K31/70
Attorney, Agent or Firm:
Masayuki Masabayashi