Title:
COMPOUND FOR TREATMENT OF NEURODEGENERATIVE DISEASE
Document Type and Number:
Japanese Patent JP2007151478
Kind Code:
A
Abstract:
To provide a polypeptide, etc., for the treatment of conformational disease.
A polypeptide contains a specific amino acid sequence and bonding to a causal protein of conformational disease to inactivate the pathogenic action of the protein; a nucleic acid encoding the polypeptide; and a recombinant expression vector or a recombinant virus containing the nucleic acid in an expressible state. The abnormality in a cell can be recovered by using a molecular mechanism of ALS onset caused by a variant SOD1 protein.
Inventors:
ICHIJO HIDENORI
SAITO HIDEKI
SAITO HIDEKI
Application Number:
JP2005352454A
Publication Date:
June 21, 2007
Filing Date:
December 06, 2005
Export Citation:
Assignee:
UNIV TOKYO
UNIV TOKYO MEDICAL & DENTAL
UNIV TOKYO MEDICAL & DENTAL
International Classes:
C12N15/09; A61K35/12; A61K35/76; A61K35/761; A61K38/00; A61K38/02; A61K48/00; A61P21/04; A61P25/16; A61P25/28; A61P43/00; C07K7/08; C07K14/47; C12N7/00; C12N7/01; C12Q1/02; G01N33/15; G01N33/50
Attorney, Agent or Firm:
Kazuo Shamoto
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Norihiro Fukasawa
Shinjiro Ono
Yasushi Kobayashi
Akio Chiba
Hiroyuki Tomita
Norihiro Fukasawa