Title:
ゲノム編集効率を増大させるための化合物
Document Type and Number:
Japanese Patent JP7319194
Kind Code:
B2
Abstract:
The present invention relates to compounds, compositions and kits suitable to precise genome editing efficiency in a eukaryotic target cell or target organism.
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Inventors:
Riesenberg, Stefan
Malichichi, Tomislav
Malichichi, Tomislav
Application Number:
JP2019555112A
Publication Date:
August 01, 2023
Filing Date:
April 10, 2018
Export Citation:
Assignee:
Max-Planck Gesellschaft Zur Fordelung der Bissenschaften E.Vau.
International Classes:
C12N15/09; A61K31/16; A61K31/194; A61K31/519; A61K31/5377; A61K31/7088; A61K31/711; A61K35/12; A61K38/45; A61K45/06; A61K48/00; A61P35/00; A61P43/00
Domestic Patent References:
| JP2016509063A |
Other References:
Genome Medicine,2015年08月27日,Vol. 7, Article number: 93
Nucleic Acids Research,2016年03月21日,Vol. 44,pp. 5204-5217, supplementary data
DNA Repair,2009年06月16日,Vol. 8,pp. 920-929, supplementary data
Nucleic Acids Research,2015年01月07日,Vol. 43,pp. 987-999, supplementary data
Nucleic Acids Research,2012年12月24日,Vol. 41,pp. 2047-2059, supplementary data
RIESENBERG, Stephan et al.,Targeting repair pathways with small molecules increases precise genome editing in pluripotent stem cells,bioRxiv preprint,2017年05月10日,doi: https://doi.org/10.1101/136374
Nucleic Acids Research,2016年03月21日,Vol. 44,pp. 5204-5217, supplementary data
DNA Repair,2009年06月16日,Vol. 8,pp. 920-929, supplementary data
Nucleic Acids Research,2015年01月07日,Vol. 43,pp. 987-999, supplementary data
Nucleic Acids Research,2012年12月24日,Vol. 41,pp. 2047-2059, supplementary data
RIESENBERG, Stephan et al.,Targeting repair pathways with small molecules increases precise genome editing in pluripotent stem cells,bioRxiv preprint,2017年05月10日,doi: https://doi.org/10.1101/136374
Attorney, Agent or Firm:
Mitsuyoshi Kamada
Hajime Takashima
Kyoko Doi
Yaeko Tamura
Hirofumi Taima
Atsuko Akai
Tomiya Tosaki
Hajime Takashima
Kyoko Doi
Yaeko Tamura
Hirofumi Taima
Atsuko Akai
Tomiya Tosaki
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