Title:
I.A.慢性関節リウマチの治療においてp38キナーゼ阻害剤として使用される縮合ヘテロアリール誘導体
Document Type and Number:
Japanese Patent JP4630662
Kind Code:
B2
Abstract:
Compounds of formula (I): wherein A is a 5-membered heteroaryl ring are inhibitors of p38 kinase and are useful in the treatment of conditions or disease states mediated by p38 kinase activity or mediated by cytokines produced by the activity of p38, such as rheumatoid arthritis.
Inventors:
Angel, richard, martin
Baldwin, Ian, Robert
Bumborough, Paul
Deboeck, niger, mark
Long Staff, Timothy
Swanson, Stephen
Baldwin, Ian, Robert
Bumborough, Paul
Deboeck, niger, mark
Long Staff, Timothy
Swanson, Stephen
Application Number:
JP2004523985A
Publication Date:
February 09, 2011
Filing Date:
July 30, 2003
Export Citation:
Assignee:
SmithKline Beechham Corporation
International Classes:
C07D209/18; A61K31/416; A61K31/427; A61K31/454; A61K31/4545; A61K31/496; A61K31/5377; A61P1/00; A61P1/02; A61P3/10; A61P9/00; A61P9/04; A61P9/10; A61P11/00; A61P11/06; A61P17/06; A61P19/00; A61P19/06; A61P21/00; A61P25/00; A61P25/08; A61P25/14; A61P25/16; A61P25/28; A61P27/02; A61P29/00; A61P33/06; A61P35/00; A61P37/08; A61P43/00; C07D231/56; C07D261/20; C07D277/82; C07D401/04; C07D403/12; C07D405/12; C07D409/04; C07D409/12; C07D413/04; C07D413/12; C07D413/14; C07D417/12; C07D417/14; A61K31/404; A61K31/4178; A61K31/42; A61K31/422; A61K31/423; A61K31/4245
Foreign References:
| WO2002055517A1 |
Attorney, Agent or Firm:
Yusuke Hiraki
Ishii Teiji
Satoshi Fujita
Ai Fujii
Ishii Teiji
Satoshi Fujita
Ai Fujii