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Title:
条件細胞培養培地とその用途
Document Type and Number:
Japanese Patent JP2004534049
Kind Code:
A
Abstract:
The invention relates to compositions comprising cell culture medium conditioned by cells grown in three-dimensional culture. The cells used to condition the medium may be genetically modified to alter the concentration of growth factors and antioxidants in the medium. The conditioned cell medium (conditioned medium) may be used for at least one of cosmetic applications, cosmeceutical applications, and pharmaceutical applications, among other things. The invention also relates to proteins comprising a heterologous sequence that enhances cell penetration. The invention also relates to cells comprising DNA encoding such proteins. Methods for preparing the inventive compounds are also provided.

Inventors:
Mansbridge, Jonathan
Application Number:
JP2003501407A
Publication Date:
November 11, 2004
Filing Date:
June 07, 2002
Export Citation:
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Assignee:
Skin Medica, Incorporated
International Classes:
C12N5/10; A61K8/35; A61K8/44; A61K8/64; A61K8/66; A61K8/67; A61K8/96; A61K8/98; A61K8/99; A61K35/12; A61K38/00; A61K38/18; A61K38/27; A61K38/39; A61K38/43; A61K38/44; A61K47/08; A61K47/20; A61K47/22; A61K47/42; A61Q19/00; C07K14/475; C07K14/52; C07K19/00; C12N5/00; C12N5/02; C12N5/08; C12N5/22; C12N15/12; C12N15/62; (IPC1-7): C07K14/475; A61K7/00; C07K14/52; C07K19/00; C12N5/10
Attorney, Agent or Firm:
Sonoda Yoshitaka
Kobayashi Yoshinori