Title:
CONTROLLED RELEASE OF STEROID FROM SUGAR COATING
Document Type and Number:
Japanese Patent JPH08231436
Kind Code:
A
Abstract:
PROBLEM TO BE SOLVED: To obtain the subject composition capable of controlling hormonal steroid release rate characteristics and its utilization in vivo and useful as compressed and sugar-coated medicinal tablets by controlling a blended amount of microcrystalline cellulose. SOLUTION: The objective composition comprises 100 wt.% of (A) a sugar (preferably white sugar), approximately 0.1-20 wt.% of (B) a hormonal steroid (e.g. medroxyprogesterone acetate, levonorgestrel, gestodene, etc.) in a charged dose and approximately 0.1-3 wt.% of (C) microcrystalline cellulose in an amount for controlling a release rate of the ingredient B. In case of a tablet, it preferably consists of a tablet core containing conjugated estrogen and the above composition.
Inventors:
REJINARUDO JIYOZEFU BAAKOUMU
Application Number:
JP368196A
Publication Date:
September 10, 1996
Filing Date:
January 12, 1996
Export Citation:
Assignee:
AMERICAN HOME PROD
International Classes:
A61K9/20; A61K9/24; A61K9/36; A61K9/28; A61K31/56; A61K31/565; A61K31/567; A61K31/57; A61K47/38; (IPC1-7): A61K47/38; A61K9/36
Attorney, Agent or Firm:
Aoyama Ryo (1 person outside)