Title:
Ｎ−アセチルノイラミン酸アルカリ金属塩・無水和物の結晶及びその製造方法
Document Type and Number:
Japanese Patent JP6867806
Kind Code:
B2
Abstract:
According to the present invention, a crystal of an alkali metal N-acetylneuraminate anhydrate, and a process for producing a crystal of an alkali metal N-acetylneuraminate anhydrate, comprising adding or adding dropwise a solvent selected from the group consisting of alcohols and ketones to an aqueous N-acetylneuraminic acid solution containing an alkali metal-containing compound and having a pH of 3.0 to 9.0 to precipitate a crystal of an alkali metal N-acetylneuraminate anhydrate, and collecting the crystal of an alkali metal N-acetylneuraminate anhydrate from the aqueous solution, can be provided.
Inventors:
Kazushige Fukumoto
Masahiro Abe
Masahiro Abe
Application Number:
JP2016538387A
Publication Date:
May 12, 2021
Filing Date:
July 29, 2015
Export Citation:
Assignee:
Kyowa Hakko Bio Co., Ltd.
International Classes:
C07H7/027
Domestic Patent References:
| JP2235897A | ||||
| JP6168418A |
Other References:
Chem.Lett.,13(6),1984,1003-1006
芦澤一英編、「医薬品の多形現象と晶析の科学 開発・製造とレギュレーションの動向」、丸善プラネット、平成14年9月20日、305-317
芦澤一英編、「医薬品の多形現象と晶析の科学 開発・製造とレギュレーションの動向」、丸善プラネット、平成14年9月20日、305-317
Attorney, Agent or Firm:
Patent business corporation glory patent office