Title:
培養容器、及び培養容器の製造方法
Document Type and Number:
Japanese Patent JP6844260
Kind Code:
B2
Abstract:
To provide a culture container capable of activating lymphocytes at an efficiency higher than conventional culture containers, as well as the production method thereof. Provided is a culture container for activating lymphocytes that is in the shape of a bag and is formed of a soft-packaging material, wherein, on one surface of opposing inner surfaces within the container, anti-CD3 antibodies are immobilized at a density of 10 to 300 ng/cm 2 , and anti-CD3 antibodies in the form of a solution are enclosed in an amount of 0.25 to 400 ng and 0.1 to 800 µl per 1 cm 2 of a culture surface formed of the one surface. Further, the bag-shaped culture container formed of a soft packaging material is produced by immobilizing anti-CD3 antibodies on one surface of opposing inner surfaces at the above-mentioned density, and enclosing the anti-CD3 antibodies in the form of a solution in the above-mentioned amount.
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Inventors:
Takahiko Toya
Tanaka Goshi
Tanaka Goshi
Application Number:
JP2016565879A
Publication Date:
March 17, 2021
Filing Date:
November 20, 2015
Export Citation:
Assignee:
Toyo Seikan Group Holdings Co., Ltd.
International Classes:
C12M3/00; C07K16/28; C07K17/08
Domestic Patent References:
| JP2010099022A | ||||
| JP2007175028A | ||||
| JP2012239401A | ||||
| JP2007056034A |
Other References:
Journal of Translational Medicine, 2010, Vol.8, No.104, pp.1-15
SEKINE T. et al.,Biomedicine & Pharmacotherapy, 1993, Vol.47, pp.73-78
OCHOA A.C. et al.,Cancer Research, 1989, Vol.49, pp.963-968
藤野 道夫、外2名.,肺癌, 1995, Vol.35, No.3, pp.253-261
SEKINE T. et al.,Biomedicine & Pharmacotherapy, 1993, Vol.47, pp.73-78
OCHOA A.C. et al.,Cancer Research, 1989, Vol.49, pp.963-968
藤野 道夫、外2名.,肺癌, 1995, Vol.35, No.3, pp.253-261
Attorney, Agent or Firm:
Heiwa International Patent Office