Cyclopropaneamine compounds and their uses

Japanese Patent JP6325449

B2

The present invention provides a compound having a lysine specific demethylase 1 inhibitory action, and useful as a medicament such as a prophylactic or therapeutic agent for schizophrenia, Alzheimer's disease, Parkinson's disease or Huntington's disease, and the like. The present invention relates to a compound represented by the formula wherein A is a hydrocarbon group optionally having substituent(s), or a heterocyclic group optionally having substituent(s); B is a benzene ring optionally having further substituent(s); R 1 , R 2 and R 3 are each independently a hydrogen atom, a hydrocarbon group optionally having substituent(s), or a heterocyclic group optionally having substituent(s); A and R 1 are optionally bonded to each other to form, together with the adjacent nitrogen atom, a cyclic group optionally having substituent(s); and R 2 and R 3 are optionally bonded to each other to form, together with the adjacent nitrogen atom, a cyclic group optionally having substituent(s), or a salt thereof.

JP7287978	two4-{[(2S)-2-{4-[5-Chloro-2-(1H-1,2,3-Triazole-1-il)Phenyl]-5-Methoxy-2-Oxopyridine-1(2H)-il}Butanoyl]amino}-2-Method for preparing fluorobenzamide derivative
JP2003506406	[Title of the Invention] A long-chain N-alkyl compound and an oxa derivative thereof.
JP2008508348	Compounds for Inhibiting Copper-Containing Amine Oxidases and Their Use

Naoki Tomita
Daisuke Tomita
Yusuke Tominari
Shinichi Imamura
Shinji Morimoto
Takuto Kojima
Masashi Toyofuku
Yasushi Hattori
Tomohiro Kaku
Mitsuhiro Ito

JP2014540921A

May 16, 2018

October 11, 2013

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Takeda GmbH

C07C237/30; A61K31/166; A61K31/167; A61K31/277; A61K31/351; A61K31/357; A61K31/381; A61K31/382; A61K31/40; A61K31/402; A61K31/4035; A61K31/415; A61K31/4155; A61K31/416; A61K31/4184; A61K31/42; A61K31/422; A61K31/425; A61K31/426; A61K31/427; A61K31/428; A61K31/429; A61K31/433; A61K31/437; A61K31/44; A61K31/4402; A61K31/4406; A61K31/4409; A61K31/4453; A61K31/4468; A61K31/454; A61K31/495; A61K31/4965; A61K31/498; A61K31/505; A61K31/506; A61K31/517; A61K31/5375; A61K31/5377; A61K31/538; A61K31/54; A61K31/55; A61P25/14; A61P25/16; A61P25/18; A61P25/28; A61P43/00; C07C237/32; C07C237/38; C07C237/40; C07C255/58; C07C255/63; C07C317/40; C07D207/14; C07D207/27; C07D209/44; C07D211/58; C07D213/40; C07D213/75; C07D223/10; C07D231/40; C07D231/56; C07D235/08; C07D239/26; C07D239/38; C07D239/52; C07D239/95; C07D241/12; C07D241/18; C07D241/42; C07D261/14; C07D265/36; C07D275/03; C07D277/28; C07D277/46; C07D277/62; C07D277/82; C07D285/08; C07D285/135; C07D295/13; C07D295/135; C07D295/192; C07D309/04; C07D309/14; C07D319/18; C07D333/20; C07D335/02; C07D401/12; C07D405/12; C07D409/04; C07D409/12; C07D413/12; C07D417/12; C07D471/04; C07D487/04; C07D513/04; C12N9/99

JP2014532619A
JP2012036124A

WO2012156531A1
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US20120004262
WO2010143582A1
WO2010084160A1
WO2010043721A1
WO2011035941A1
WO2011042217A1
WO2012135113A1
WO2012013728A1
WO2011131697A1

Takashima Ichi
Kyoko Doi
Mitsunori Kamata
Yaeko Tamura
Murata Miyuki
Junzo Koike
Hirofumi Toma

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