Title:
DDHOMOSTEROID
Document Type and Number:
Japanese Patent JPS53132553
Kind Code:
A
Abstract:
D-homopregnanes of the formula I wherein R6 is hydrogen, chloro, fluoro or methyl; X is beta -hydroxymethylene or carbonyl; R17a is hydroxy, lower alkanoyloxy or aroyloxy; R21 is hydrogen, chloro, fluoro, hydroxy, lower alkanoyloxy, aroyloxy, sulfate or phosphate; and the dotted line in the 1,2-position of the A-ring denotes an additional carbon-carbon bond AND PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, PROCESSES FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AS THE ACTIVE INGREDIENT ARE DISCLOSED. The D-homopregnanes of the present invention exhibit hormonal activity and are useful for the treatment of inflammation.
Inventors:
REO ARIKU
ANDORU FUYURUSUTO
MARUSERU MIYUURAA
URURITSUHI KERUBU
RUDORUFU BIIHIYAATO
ANDORU FUYURUSUTO
MARUSERU MIYUURAA
URURITSUHI KERUBU
RUDORUFU BIIHIYAATO
Application Number:
JP4544478A
Publication Date:
November 18, 1978
Filing Date:
April 19, 1978
Export Citation:
Assignee:
HOFFMANN LA ROCHE
International Classes:
A61K31/215; A61K31/22; A61K31/57; A61P29/00; A61K31/12; C07J63/00; (IPC1-7): A61K31/12; A61K31/22; A61K31/66; C07J63/00