【発明の名称】筋肉内および皮内投与のためのポリヌクレオチド組成物

Title:

【発明の名称】筋肉内および皮内投与のためのポリヌクレオチド組成物

Document Type and Number:

Japanese Patent JP2002536399

Kind Code:

A

Abstract:

Compositions and methods for intramuscular administration of polynucleotides, such as RNA, DNA, or derivatives thereof comprising polynucleotides and block copolymers of alkylethers. The invention also provides compositions and methods for stabilizing polynucleic acids and increasing the ability of polynucleic acids to cross cell membranes and act in the interior of a cell.

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Inventors:

Kabanov, Alexander, Buoy.
Remieu, Pierre, M.
Vinogradov, Sir Jay, Buoy.
Arakov, Valerie Wye.

Application Number:

JP2000598139A

Publication Date:

October 29, 2002

Filing Date:

January 06, 2000

Export Citation:

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Assignee:

Splatec Pharma Inc.
Kabanov, Alexander, Buoy.

International Classes:

A61K9/06; A61K9/00; A61K9/107; A61K39/12; A61K39/21; A61K39/245; A61K47/30; A61K47/34; A61K47/48; A61K48/00; C08F290/00; C08F297/00; C08L51/00; C08L53/00; C08L71/02; A61K9/51; (IPC1-7): A61K48/00; A61K9/06; A61K47/30; A61K47/34

Attorney, Agent or Firm:

Mikio Hatta (4 outside)

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