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Title:
DETECTION OF TOXOPROTEIN PRODUCED BY MRSA, MONOCLONAL ANTIBODY AND ITS FRAGMENT, KIT FOR DETECTING TOXOPROTEIN PRODUCED BY MRSA AND HYBRIDOMA CAPABLE OF PRODUCING MONOCLONAL ANTIBODY
Document Type and Number:
Japanese Patent JP2000316574
Kind Code:
A
Abstract:

To rapidly and simply detect a toxoprotein with high degree of reliability by using an antibody having the ability to specifically bind to a toxoprotein produced by a methicillin-resistant Staphylococcus aureus(MRSA).

An antibody having the ability to specifically bind to a toxoprotein produced by MRSA such as a monoclonal antibody is used to detect the toxoprotein produced by the MRSA. Furthermore, the monoclonal antibody is preferably specific for leukocidin F which is the toxoprotein produced by the MRSA or is preferably produced by a hybridoma (FERM BP-6669) prepared by cell fusion of an animal cell immunized with the leukocidin F to a cell of a myeloma of the animal, preferably has the ability to specifically bind to the leukocidin F and is preferably labeled with an enzyme, a radioisotope, a fluorescent coloring matter, biotin, etc.


Inventors:
NAKANO OSAHISA
KAMATA YOICHI
KAMIO YOSHIKORE
NIWA KAZUHIRO
ONOUCHI TORU
GOTO YUICHI
Application Number:
JP2000059946A
Publication Date:
November 21, 2000
Filing Date:
March 06, 2000
Export Citation:
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Assignee:
MATSUSHITA SEIKO KK
OSAKA PREFECTURE
International Classes:
G01N33/569; C07K14/31; C07K16/12; C12N5/10; C12N15/02; C12P21/02; C12P21/08; G01N33/543; G01N33/577; (IPC1-7): C12N15/02; C07K16/12; C12N5/10; C12P21/08; G01N33/569; G01N33/577
Attorney, Agent or Firm:
Fumio Iwahashi (2 others)