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Title:
試料における干渉物質の決定
Document Type and Number:
Japanese Patent JP7153019
Kind Code:
B2
Abstract:
A method for determining a non-anticoagulant interferent in a blood-derived sample of a subject, the method comprising a) determining a value of a coagulation time-related parameter in the sample; b) comparing the value of the coagulation time-related parameter determined in a) to a value of the coagulation time-related parameter determined in at least one reference sample; and c) based on the result of comparison step b), determining the non-anticoagulant interferent in a blood-derived sample of a subject. A method for identifying a blood-derived sample having insufficient quality is further disclosed, the method comprising determining non-anticoagulant interferent(s) according to the aforesaid method.

Inventors:
Richte, andrea
Town, Michael-Harold
Application Number:
JP2019528040A
Publication Date:
October 13, 2022
Filing Date:
December 13, 2017
Export Citation:
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Assignee:
F. HOFFMANN-LA ROCHE AKTIENGESELLSCHAFT
International Classes:
G01N33/72; C12M1/34; C12N9/02; C12N9/14; C12N9/50; C12Q1/26; C12Q1/34; C12Q1/37; G01N33/86
Domestic Patent References:
JP7231795A
JP2003319797A
JP51005600B1
JP3010696A
Foreign References:
US6326208
CN105866445A
CN101666806A
Other References:
NOWELL, S. A. et al.,Identification of Enzymes Responsible for the Metabolism of Heme in Human Platelets,JOURNAL OF BIOLOGICAL CHEMISTRY,The American Society for Biochemistry and Molecular Biology,1998年12月11日,vol.273, No.50,pp.33342-33346
KOPEC, M. et al.,The antithrombin activity of glucuronic esters of bilirubin,JOURNAL OF CLINICAL PATHOLOGY,1961年09月01日,vol.14, No.5,pp.478-481
Attorney, Agent or Firm:
Osamu Yamamoto
Toru Miyamae
Motoharu Nakanishi