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Title:
次亜リン酸誘導体のジアステレオ異性体
Document Type and Number:
Japanese Patent JP2012520870
Kind Code:
A
Abstract:
The invention relates to the diastereoisomers of hypophosphorous acid derivatives, having formula (I), wherein the phenyl group is substituted by one or several atoms or groups, occupying one or several positions on the phenyl ring, and a method for the separation thereof.

Inventors:
Asher Francine
Cervin Celia
Pan Jean-Philippe
Application Number:
JP2012500362A
Publication Date:
September 10, 2012
Filing Date:
March 19, 2010
Export Citation:
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Assignee:
Saintur Nacional De La Rousche Châtantique Séenneres
International Classes:
C07F9/30; A61K31/662; A61P43/00; G01N30/20; G01N30/26; G01N30/32; G01N30/74; G01N30/88; C07B57/00
Domestic Patent References:
JP2009511624A2009-03-19
Other References:
JPN6014026982; LIU,X. et al.: 'Enantioselective synthesis of phosphinyl peptidomimetics via an asymmetric Michael reaction of phosp' Journal of Organometallic Chemistry Vol.646, 2002, p.212-222
JPN6014026983; LAMMERHOFER,M. et al.: 'High-performance liquid chromatographic enantiomer separation and determination of absolute configur' Tetrahedron Asymmetry Vol.14, No.17, 2003, p.2557-2565
JPN6014026984; KOVAL,D. et al.: 'Separation of diastereomers of phosphinic pseudopeptides by capillary zone electrophoresis and rever' Journal of Separation Science Vol.26, 2003, p.653-660
Attorney, Agent or Firm:
Norihiko Hibi
Einosuke Kishimoto
Akira Watanabe
Matsumura Naoto