Title:
二量体IAP阻害剤
Document Type and Number:
Japanese Patent JP2014501235
Kind Code:
A
Abstract:
The present invention provides compounds of formula M-L-M' (where M and M' are each independently a monomeric moiety of Formula (I), (II), (III) or (IV) and L is a linker). The dimeric compounds have been found to be effective in promoting apoptosis in rapidly dividing cells.
Inventors:
Christopher Shawn Strob
Chen Zhuang
Chen Zhuang
Application Number:
JP2013543719A
Publication Date:
January 20, 2014
Filing Date:
December 13, 2011
Export Citation:
Assignee:
Novartis Age
International Classes:
C07K5/062; A61K31/337; A61K38/00; A61K39/395; A61K45/00; A61P35/00; A61P43/00
Attorney, Agent or Firm:
Aoyama Aoi
Takuji Yamada
Michiko Matsutani
Yasushi Ochiai
Takuji Yamada
Michiko Matsutani
Yasushi Ochiai