ENGINEERED NATURAL KILLER (NK) CELLS, AND COMPOSITIONS AND METHODS THEREOF

Title:

ENGINEERED NATURAL KILLER (NK) CELLS, AND COMPOSITIONS AND METHODS THEREOF

Document Type and Number:

Japanese Patent JP2023089054

Kind Code:

A

Abstract:

To provide engineered Natural Killer (NK) cells and methods of producing engineered NK cells.SOLUTION: The present invention provides an engineered natural killer (NK) cell, wherein the NK cell is genetically engineered to reduce FcRγ chain expression, activity and/or signaling in the cell. The engineered NK cells and compositions containing the engineered NK cells are useful for treating diseases such as cancer.SELECTED DRAWING: Figure 1

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Inventors:

GUY DIPIERRO

Application Number:

JP2023060549A

Publication Date:

June 27, 2023

Filing Date:

April 04, 2023

Export Citation:

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Assignee:

INDAPTA THERAPEUTICS INC

International Classes:

C12N15/09; A61K35/17; A61K39/395; A61K45/00; A61K47/02; A61K47/36; A61K47/42; A61P29/00; A61P31/04; A61P31/12; A61P35/00; A61P35/02; A61P43/00; C12N1/00; C12N1/02; C12N5/0783; C12N5/10; C12N15/113

Attorney, Agent or Firm:

Hatsushi Shimizu
Hirotaka Yamaguchi
Shun Jinbe
Ryuichi Inoue
Toshimitsu Sato
Koichi Niimi
Tomohiko Kobayashi
Hideki Kodera
Masato Ozeki
Kazuya Kawamoto

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