Title:
FGFR-Fc fused protein and its use
Document Type and Number:
Japanese Patent JP6138304
Kind Code:
B2
Abstract:
PROBLEM TO BE SOLVED: To construct an FGFR-Fc fusion protein capable of antagonizing FGF.SOLUTION: A fusion protein comprises: a moiety of an intermediate functional sequence (IFS) of an Ig-like domain of FGFR, a second Ig domain (D2) of FGFR, a third Ig-like domain (D3) of FGFR, and an immunoglobulin Fc region.SELECTED DRAWING: Figure 1
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Inventors:
Fan janmin
Redon
Redon
Application Number:
JP2016038502A
Publication Date:
May 31, 2017
Filing Date:
March 01, 2016
Export Citation:
Assignee:
Yantai Rongchan Biotechnology Company Limited
International Classes:
C07K19/00; A61K31/711; A61K38/00; A61K38/16; A61K48/00; A61P35/00; C07K14/71; C07K16/46; C12N5/10; C12N15/09; C12P21/02
Foreign References:
| WO2000046380A1 |
Other References:
Cytokine Growth Factor Rev.,2005年,Vol. 16,p. 139-149
J. Biol. Chem.,1995年,Vol. 270,. No. 17,p. 10231-10235
Proc. Natl. Acad. Sci. USA,2004年,Vol. 101, No. 4,p. 935-940
J. Biol. Chem.,1995年,Vol. 270,. No. 17,p. 10231-10235
Proc. Natl. Acad. Sci. USA,2004年,Vol. 101, No. 4,p. 935-940
Attorney, Agent or Firm:
Atsushi Nakajima
Kato Kazunori
Kato Kazunori