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Title:
FDG SYNTHESIZER USING DISPOSABLE CARTRIDGE
Document Type and Number:
Japanese Patent JP3133250
Kind Code:
B2
Abstract:

PROBLEM TO BE SOLVED: To provide a FDG(fluorodeoxyglucose) synthesizer simplified in the preparative operation and production process for FDG synthesis, capable of improving synthesis yield and shortening synthesis time, and facilitating FDG quality nuiformization and control.
SOLUTION: This FDG synthesizer is so designed that a disposable cartridge section 30 is equipped with a cartridge-type resin column 4 for labeling reaction designed to trap F-18 anions contained in target water and then carry out a labeling reaction between the F-18 anions and triflate and consisting of a column packed with an immobilized phase-transfer catalyst resin, and a cartridge-type cation exchange resin column 17 designed to bring an intermediate formed by the labeling reaction into contact with a H+ type-modified cation exchange resin to carry out a hydrolysis reaction of the intermediate, and integrated with a line and a changeover valve for communication between the resin columns 4 and 17.


Inventors:
Shigeki Yamazaki
Katsuhiko Ohsaki
Application Number:
JP7553396A
Publication Date:
February 05, 2001
Filing Date:
March 29, 1996
Export Citation:
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Assignee:
Nuke-Ke-Plant Construction Co., Ltd.
Nippon Steel Tube Co., Ltd.
International Classes:
C07H5/02; A61K51/00; C07B59/00; (IPC1-7): C07H5/02; C07B59/00
Domestic Patent References:
JP55143999A
JP7507813A
Other References:
Nucl.Med.Biol.,Vol.17,No.3(1990)p.273−279
Attorney, Agent or Firm:
Yasuo Ishikawa