To provide fine particles enclosing a fat-soluble medicine by using a biodegradable porous inorganic fine particles, especially biodegradable porous hydroxyapatite as a carrier, and capable of obtaining good absorbability in a living body by especially non-orally administration such as administration by injection, etc., or by oral administration, a method for producing the same and a preparation containing the same.
The fine particles enclosing the fat-soluble medicine are characterized by enclosing the fat-soluble medicine in the biodegradable porous hydroxyapatite fine particles having 1-20 μm mean particle diameter, and it is possible to make an injection agent capable of being administered intravenously, subcutaneously or intramuscularly by dispersing the particles with a dispersing agent such as carboxymethylcellulose (CMC), etc., and the absorbability of them in the living body is excellent.
ISHIHARA TSUTOMU
SHIMADA EMI
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