HCV REGULATED PROTEIN - HOFFMANN LA ROCHE

Title:

HCV REGULATED PROTEIN

Document Type and Number:

Japanese Patent JP2005047895

Kind Code:

A

Abstract:

To provide a method that is useful for therapy and diagnosis of HCV (hepatitis C virus) infection, particularly provide a method for screening the predictive marker of the disinfection prognosis and the compound regulating the activity or expression of the target by specifying the factor originating from the host cells that can become the target of the therapeutic agent.

At least one polypeptide that comprises at least one of a specific polypeptide selected from the HCV replicon regulating polypeptide originating from the host cells is useful as a target for anti-HCV and as a predictive marker of the prognosis. This invention further provide a method for evaluating in vitro a compound that regulates the activity or expression and is displayed in the form of medicines or diagnostic kits whereby they can be provided as therapeutic medicines or diagnostic agents.

Inventors:

BERNDT PETER
KILBY PETER MICHAEL
RUGMAN PAUL

Application Number:

JP2004192804A

Publication Date:

February 24, 2005

Filing Date:

June 30, 2004

Export Citation:

Click for automatic bibliography generation Help

Assignee:

HOFFMANN LA ROCHE

International Classes:

G01N33/50; A61K45/00; A61P31/14; C07K14/18; C07K14/47; C07K16/10; C12Q1/02; G01N33/15; G01N33/53; G01N33/566; (IPC1-7): C07K14/18; A61K45/00; A61P31/14; C07K16/10; C12Q1/02; G01N33/15; G01N33/50; G01N33/53; G01N33/566

Attorney, Agent or Firm:

Hajime Tsukuni
Fumio Shinoda

Previous Patent: POROUS PARTICLE LOADED WITH COSMETICALLY OR PHARMACEUTICALLY ACTIVE COMPOUND

Next Patent: ANTI-CHLAMYDIAL COMPOSITION